From gene to large scale protein expression in record time and quality.
Find out how ExcellGene can create value for your company.
About excellgeneExcellGene SA is an established, science and technology driven Service Provider to the Pharma/Biotech industry. It pioneered innovative technologies resolving problems of expression and manufacture of recombinant proteins from mammalian cells. ExcellGene's technologies cover vectors, gene transfer systems, cell hosts, screening platforms for cells and processes, scale-up principles and bioreactors. ExcellGene provides superior solutions for protein manufacturing processes based on mammalian cells. We offer services to industry and academic institutions whereby we assist in all steps that are necessary to move a DNA "concept" to the reality as a purified protein. ExcellGene has been the innovative driver and developer for cell culture equipment and tools that have been successfully marketed by ExcellGene's partners Kühner AG (incubator shakers), TPP (TubeSpin® High Trough-Put Bioreactor, PCV tube - biomass determination) and Sartorius-Stedim (Cultiflask 50plus). Additional highly innovative technologies and instruments are in development, such as the Orb-Shake bioreactor 200 (50-200 Liter working volume) and the Orb-Shake bioreactor 1500 (300-1500 Liter working volume). |
New Record Achieved:More than 1 Gram / Litre Yield in Transient Expression of Proteins.ExcellGene scientists accomplished an important breakthrough in recombinant antibody production based on transient gene expression (TGE) in mammalian cells. With TGE the DNA encoding the protein of interest is directly used as an ingredient in the manufacturing process allowing for fast production of recombinant proteins. As a result gram and kilogram quantities of proteins can be produced within weeks instead of months. Building further on its strength in transient gene expression and orbital shaking bioreactors at the 1,000 litre scale, ExcellGene is in the process of establishing a GMP facility to further meet the needs of its customers. See our recent press release. |







