Cloning of CHO Cells, Productivity and Genetic Stability – a Discussion

Cloning of CHO Cells, Productivity and Genetic Stability – a Discussion AbstractWhile many perceive mammalian cell culture-based manufacturing for biopharmaceuticals an established technology, numerous open questions remain to be solved. Genetic diversity and mutation...

Better media and feeds for higher CHO yield

Better media and feeds for higher CHO yield NEWS In an article written in November 2017 by Dr. Angelo DePalma in Genetic Engineering and Biotechnology News, ExcellGene and Prof. F. Wurm were referred to discussing the benefits of better media and feeds as the main...

Cloning of CHO Cells, Productivity and Genetic Stability – A discussion

AuthorsFlorian M. Wurm 1, 2 and Maria João Wurm 2, * 1 Swiss Federal Institute of Technology Lausanne (Prof. Emeritus), Route Cantonale, 1015 Lausanne, Switzerland 2 ExcellGene SA, Route de l’Ile-au-Bois 1A, 1870 Monthey, Switzerland * Previous publications under...

CHO Quasispecies – Implications for Manufacturing Processes

AuthorFlorian M. Wurm 1, 2, * 1 Swiss Federal Institute of Technology Lausanne (Prof. Emeritus), Route Cantonale, 1015 Lausanne, Switzerland 2 ExcellGene SA, Route de l’Ile-au-Bois 1A, 1870 Monthey, Switzerland Academic EditorDavid L. Hacker PublishedProcesses, 2013,...