White Paper: CHO Quasispecies – Implications for Manufacturing Processes Now Available The White Paper CHO Quasispecies – Implications for Manufacturing Processes is now freely available for viewing on our website. First published in Processes Journal in 2013, it has...
CHO Quasispecies – Implications for Manufacturing Processes AbstractChinese hamster ovary (CHO) cells are a source of multi-ton quantities of protein pharmaceuticals. They are, however, immortalized cells, characterized by a high degree of genetic and phenotypic...
Cloning of CHO Cells, Productivity and Genetic Stability – a Discussion AbstractWhile many perceive mammalian cell culture-based manufacturing for biopharmaceuticals an established technology, numerous open questions remain to be solved. Genetic diversity and mutation...