CHO Quasispecies – Implications for Manufacturing Processes AbstractChinese hamster ovary (CHO) cells are a source of multi-ton quantities of protein pharmaceuticals. They are, however, immortalized cells, characterized by a high degree of genetic and phenotypic...
Cloning of CHO Cells, Productivity and Genetic Stability – a Discussion AbstractWhile many perceive mammalian cell culture-based manufacturing for biopharmaceuticals an established technology, numerous open questions remain to be solved. Genetic diversity and mutation...
