Careers

ExcellGene is a privately owned contract research, development and manufacturing organization (CDMO) based in Monthey, Switzerland and Boston, Massachusetts, USA. ExcellGene’s unique transient and stable protein expression technologies together with extensive knowledge and experience in the biotech field cover broad value chain for its clients: from DNA construction and transfection to bioprocess development of scalable and GMP-compliant protein production processes. ExcellGene’s technology is one of the most advanced for rapid production of recombinant proteins and up to several grams of product delivered within weeks.

Available roles


Manufacturing/Engineering Specialist

Posted 30th March 2021, updated 18th November 2021

This position is permanent and full-time, and to start immediately.

Job description

Performing production-related tasks as assigned by the group lead. These tasks can include, but are not limited to, manufacturing tasks, quality tasks, facilities maintenance requirements, ordering of supplies, materials, and equipment for production.

The position is divided in the following fields of activities:

Manufacturing

The Manufacturing Specialist will support the cGMP cell banking unit with the planning and execution of all process steps of mammalian cell banking manufacturing from cell culture to filling including viability studies for cell banks. In cell banking he/she will be in the lead for preparation of master and working cell banks.

Engineering

The Engineering Specialist will support the installation, operation, maintenance and/or troubleshooting of manufacturing equipment such as washers, autoclaves, incubators, microbiological safety cabinets, ultracold freezers etc. He/She develops Standard Operating Procedures, Preventive Maintenance plans, calibration procedures, process descriptions and validation testing plans as requested. Monitor and control maintenance operations to achieve the targeted turn-around time within required quality standards.

Additional tasks include:

  • Supporting the team in the implementation and application of Quality Management System.
  • Evaluating test results, reviewing production documentation, working on deviations, change requests, supports risk assessments and the implementation of CAPAs (Corrective And Preventive Actions) to ensure high-quality GMP standards.
  • Creating documentation for each task, including manufacturing process, aseptic processing techniques, Good Manufacturing Practices (GMP), cleaning procedures and clean room safety practices and procedures.
  • Improvement of the MCB documentation (method and SOPs, records, validation and verification procedures for existing methods).
  • Implementation/support for implementation of diverse new or improved systems within cell banking, wherever applicable.
  • Assist in training new and existing employees on the cell banking unit.
  • Assist in providing positive and constructive individual feedback and building teamwork.

Required skills

  • Relevant hands-on experience in mammalian cell culture and cell banking activities under cGMP.
  • Good technical understanding of manufacturing processes and associated equipment.
  • General knowledge of clean room practices and familiarity with Current Good Manufacturing Practices (cGMP) preferred
  • Experience in maintenance of building management system preferred.
  • Accountable for assisting in the identification, development, and implementation of new systems which enhances the operation and/or engineering processes.
  • Must be aware of requirement specifications from an equipment qualification perspective (IC/OC, IQ/OQ, CRs, etc.)
  • Good knowledge and interpretation of cGMP, ISO, FDA, MHRA and Pharmacopeia requirements, and good documentation practices.
  • Capacity to establish written documentation on procedures, results, observations, including reports and documents that are required for regulatory purposes.
  • Experience in writing and/or revising SOP’s, batch records, and other Quality/Compliance related documents.
  • Strong interpersonal and leadership skills and abilities to drive projects towards completion under time and resources constrains.
  • Structured, focused and well-organized working attitude.
  • Must be detail-oriented with an ability to set priorities, and organize daily work requirements
  • Open-minded for new ideas and suggestions
  • Organizational and problem-solving skills, attention to detail and autonomy.
  • With strong sense of discipline and with initiative with hands-on approach to work.
  • Good communication skills.
  • Generally independent, but with ability to work in teams.
  • Fluency in English, oral French is plus.
  • Understanding of MS Office applications.

Mandatory requirements

  • Educational background required: Bachelor or Master Degree in biotechnology, biochemistry, life sciences or related discipline.
  • 1-3 years of experience with mammalian cell culture.
  • 1-3 years of supervisory/management experience, having a sound knowledge of aseptic processing, cell culture, engineering and compliance with GMP rules.
  • Ability to work in a time driven environment and to manage multiple priorities.
Apply for this position

Cell Line Development Associate

Posted 2nd Nov 2021

This position is permanent and full-time, and to start immediately.

Job description

  • Plan and perform cell culture activities with suspension-adapted mammalian CHO cell lines for stable cell line generation and optimization:
    • Seed maintenance and expansion
    • Transfection for Transient Gene Expression and Stable Pool Generation
    • Recombinant pool selection
    • Single cell cloning
    • Batch and fed-batch cultures in non-instrumented small-scale bioreactors
  • Keep an up-to-date written and electronic record of executed laboratory work
  • Prepare project progress reports in form of PowerPoint presentation and final project report
  • Data analysis and presentation internally and to external Clients
  • Provide support to Head of Cell Line Development (if needed)
  • This position is to report directly to Head of Cell Line Development.

Required skills

  • Hands-on experience in mammalian cell culture
  • Hands-on recombinant protein production in mammalian cells (transient and/or stable)
  • Proficiency of MS Office applications
  • Molecular biology skills are plus
  • Organizational skills
  • Good communication skills
  • Generally independent, but with ability to work in teams
  • Willingness to learn and grow professionally.

Mandatory requirements

  • Master Degree in biotechnology, cell biology, molecular biology or related discipline
  • 1-3 years of experience with mammalian cell culture
  • Fluency in English, oral French is plus.
Apply for this position

Senior Associate — Down Stream Processing (DSP biologics)

Posted 2nd Nov 2021

This position is permanent and full-time, and to start immediately.

Job description

  • Planning and execution of DSP development/characterization of biosimilar/biologics drug substance in pre-clinical and clinical phases including development of scale-down models and scale-up procedures, reporting to the Head of DSP.
  • Execution of generic purifications at lab scale, mid-scale, and large-scale levels to deliver purified proteins according to expected specifications, including production of non-GMP lots for Tox studies.
  • Writing of protocols, reports, recording, management and evaluation of raw data/analyses/results, forming of sound scientific conclusions and providing suitable follow-up activities.
  • Development and optimization of DSP methods/processes, implementation of new technologies, search/utilization of knowledge from scientific and technical literature.
  • Leading DSP activities within project technical teams to deliver purified material for internal and/or external client.
  • Prompt communication of achievements, risks, issues in all areas and contribution to root cause investigations and troubleshooting.
  • Maintenance of high standards of quality, cleanliness, and organization within the laboratory environment.
  • Preparation of process development report and presentations for internal and/or external client meetings.

Required skills

  • Strong knowledge in downstream processing concepts and implementation strategies (e.g., buffer preparation, chromatography, TFF, Kr2i/Äkta systems).
  • Strong knowledge and solid hands-on experience in chromatography-based protein purification (e.g., affinity, ion-exchange, hydrophobic interactions, size-exclusion) and filtration-based separation methods for biologics.
  • Knowledge in high-throughput DSP development and DoE is a plus.
  • Scientifically curious, proactive, willing to learn, flexible, and with attention to details.
  • Rigorousness, strong sense of discipline and attention to details.
  • Problem-solving and hands-on approach to work.
  • Autonomous and able to work both independently and as part of a multicultural team within a matrix organization.
  • Flexibility and ability to adapt to changes in a fast-paced and dynamic environment.
  • Excellent communication skills. Good written and oral French and English languages.

Mandatory requirements

  • Minimum B.Sc., M.Sc. preferred or PhD. in Biotechnology, Biology, Chemistry or related field.
  • At least 4 years of relevant experience in DSP development and/or manufacturing.
Apply for this position

Lab Technician — Downstream Processing

Posted 2nd Nov 2021

This position is permanent and full-time, and to start immediately.

Job description

  • Plan and perform generic purifications at lab scale, mid-scale, and large-scale levels to deliver purified proteins according to expected specifications, including production of non-GMP lots for Tox studies, reporting to the Head of DSP
  • Preparation of mobile phases/buffers, aliquoting of drug substances
  • Writing of protocols, reports, recording, forming of sound scientific conclusions
  • Support development and optimization of DSP methods/processes, implementation of new technologies, search/utilization of knowledge from scientific and technical literature
  • Prompt communication of achievements, issues in all areas and contribution to troubleshooting
  • Maintenance of high standards of quality, cleanliness, and organization within the laboratory environment.

Required skills

  • Knowledge and hands-on experience in chromatography-based protein purification (e.g., affinity, ion- exchange) and filtration-based separation methods for biologics
  • Scientifically curious, proactive, willing to learn, flexible, and with attention to details
  • Problem-solving and hands-on approach to work
  • Autonomous and able to work as part of a multicultural team within a matrix organization
  • Ability to adapt to changes in a fast-paced and dynamic environment
  • Good communication skills. Good written and oral skills for French & English languages.

Mandatory requirements

  • Minimum technical degree (“CFC Laborantin”) to B.Sc. in biotechnology, biochemistry, molecular biology or related field.
Apply for this position

Research Associate — Analytics (HPLC and CE)

Posted 18th Nov 2021

This position is permanent and full-time, and to start immediately.

Job description

Under the supervision of the of the Head of Analytics, the candidate will actively participate in laboratory activities including but not limited to:

  • The operation of (U)HPLC and CE systems for protein analytics, including sample preparation, method/process troubleshooting and instrument preventive maintenance.
  • The design and execution of experimental assays using different analytical techniques and following established operating procedures, including data analysis and presentation.
  • The active support in the development of analytical methods and processes, the implementation of new technologies, the writing of protocols and technical reports according to corporate guidelines and quality standards.

Required skills

  • Excellent understanding of analytical chemistry and protein biochemistry.
  • Solid hands-on experience in protein analysis by liquid chromatography (HPLC andr UHPLC), with particular focus on affinity chromatography (protein A/G/L, etc.), SEC/GPC, RP and HILIC. Expertise in the operation of DLS/MALS detectors (including data analysis and interpretation) would be a strong plus.
  • Prior experience with capillary electrophoresis techniques (CE-SDS, cIEF, CZE, etc.) would be an advantage.
  • Excellent computer skills (MS Office package, basic statistical data analysis, familiar with the use of control and analytical software for chromatography instruments).
  • Scientific curiosity, proactiveness, initiative and willingness to learn.
  • Rigorousness, strong sense of discipline and attention to details.
  • Problem-solving and hands-on approach to work.
  • Autonomous and able to work both independently and as part of a multicultural team within a matrix organization.
  • Flexibility and ability to adapt to changes in a fast-paced and dynamic environment.
  • Excellent communication skills. Good written and oral French and English.

Mandatory requirements

  • Minimum B.Sc., M.Sc. or higher preferred in Biotechnology, Biology, Chemistry or related field.
  • Proven previous experience in analytics within R&D, analytical or QC laboratories (preferably 1-3 years within the industrial environment or in academia with at least 5 years of post-graduate work experience).
Apply for this position

Senior Lab Technician — Analytics (CFC)

Posted 18th Oct 2021, updated 18th Nov 2021

This position is permanent and full-time, and to start immediately.

Job description

Under the supervision of the of the Head of Analytics, the candidate will actively participate in laboratory activities including but not limited to:

  • The preparation of chemicals and solutions and their delivery and efficient turnover for each experiment.
  • In coordination with the Procurement Dept., being responsibile for the purchasing of all the chemicals and analytical supplies, including searching for the best available alternatives and pricing.
  • The supervision and frequent update of the inventory database of chemicals (including proper labelling according to EHS procedures), consumables and small laboratory equipment (including the planning and implementation of their maintenance and calibration).
  • The receival, tracking and management of the test samples and consumables.
  • The handling and preparation of biological samples.
  • The execution of experimental assays using different analytical techniques and following established operating procedures.
  • The recording and analysis of experimental data following corporate guidelines and quality standards.
  • The orientation, training and supervision of apprentices, students and part-time laboratory workers.

Required skills

  • Very good understanding of molecular biology and protein biochemistry.
  • Excellent project and time management skills.
  • Prior experience with Quality Management Systems and ISO accreditation would be a strong plus.
  • Excellent computer skills (MS Office package, database handling and basic statistical data analysis).
  • Rigorousness, strong sense of discipline and attention to details.
  • Problem-solving and hands-on approach to work.
  • Generally autonomous and able to work both independently and as part of a multicultural team within a matrix organization.
  • Flexibility and ability to adapt to changes in a fast-paced and dynamic environment.
  • Excellent communication skills. Good written and oral French and English.

Mandatory requirements

  • Minimum CFC preferred in Biotechnology, Biology, Chemistry or related field.
  • Proven previous experience in analytics within R&D, analytical or QC laboratories (preferably 3-5 years within the industrial/clinical environment or in academia as lab manager or equivalent).
Apply for this position

Research Associate — Up Stream Processing / STR Development

Posted 4th October 2021

This position is permanent and full-time, and to start immediately.

Job description

  • Plan and perform cell culture experiments with suspension-adapted mammalian cell lines, CHO and HEK.
  • STR scale-up from 1L to 200L pilot scale
  • Design & conduct experiments, data analysis and presentation internally and to external Clients
  • Keep an up-to-date written and electronic record.
  • Prepare project progress reports in form of PPT and final project report.
  • This position is to report to Head of Operations.

Required skills

  • Hands-on experience in mammalian cell culture, as well as protein production from mammalian cells (transient and/or stable)
  • Molecular biology skills are plus.
  • Proficiency with MS Office applications.
  • Organizational and problem-solving skills, attention to detail and autonomy.
  • With strong sense of discipline and with initiative with hands-on approach to work.
  • Good communication skills.
  • Generally independent, but with ability to work in teams.
  • Willingness to learn and grow professionally
  • Fluency in French, oral English is plus.

Mandatory requirements

  • Educational background required: Master Degree in biotechnology, biochemistry, molecular biology or related discipline
  • 1-3 years of experience with mammalian cell culture.
Apply for this position

Head of Procurement

Posted 15th September 2021

This position is permanent and full-time, and to start immediately.

Job description

In order to support our operations, you will take the lead of our Procurement department and manage a small team. You will:

  • Evolve in a highly technical environment
  • Establish supply agreements with our strategic supply partners, insuring optimal availability and prices of our consumables and equipment
  • Assist our specialist in finding new products and purchasing channels
  • Participate in qualification audits of our suppliers
  • Improve internal processes (planning, warehousing, production and budget…)
  • Be involved in strategic projects.

Required skills

  • Very good technical understanding of Biotech or Pharmaceutical environment
  • Higher technical educational degree with specialization in purchasing
  • Excellent negotiation skills
  • Used to standards such as ISO and specifications applied in Pharma and Biotech
  • Confirmed experience in project management
  • Flexibility and ability to adapt in a fast-paced and dynamic environment
  • Curiosity, proactiveness, initiative and willingness to learn
  • Problem-solving and hands-on approach to work
  • Excellent communication skills. Good written and oral French and English

Mandatory requirements

  • Technical background preferentially in Biotech ore pharmaceutical environment
  • Proven previous experience in a similar position
Apply for this position

Business Development Manager, North America East Coast

Posted 18th June 2021

Job description

We are recruiting a Business Development Manager for our growing Commercial Team. Our mission is to provide great science to clients in the Pharma and biotechnology industries. This individual will create client opportunities and establish partnerships with companies in striving for them to become key accounts in the territory. The ideal individual has a solid track record in managing relationships, external and internal, to exceed business development objectives.

This position is permanent and full-time, and to start immediately.

Job description

  • Develop and implement Business Development strategies for growing our cell line development services in human and animal health.
  • Identify opportunities and convert leads to expand our customer base. Our customers include those targeting any protein of interest in the fields of therapeutics and vaccine.
  • Perform effective business development and negotiation processes to establish a strong pipeline of accounts with cell line development contracts.
  • Promote the licensing of ExcellGene’s technologies and selling transfection-related products.
  • Manage business forecasts and budgetary input.
  • Work closely with other colleagues of the Commercial Team.

Required skills

  • Extensive experience in CRO, CRDO, or CDMO in identifying and working with decision makers in the biopharmaceutical and biotech industries.
  • Experience in market analysis, assessment of competitions, and a solid understanding of customers in the biopharmaceutical and biotech industries.
  • Strong knowledge in how to obtain leads and penetrate the CDMO markets.
  • Knowledge in cell line development, upstream, and downstream process developments.
  • Understanding of customer-centric business development and selling.
  • Ability to clearly communicate with customers and inside resources to accomplish objectives.
  • Ability to maintain accurate information in CRM and document related management tools.
  • Rigorousness, strong sense of discipline and attention to detail.
  • A hands-on approach to problem-solving and ability to flexibly adapt to changes in a fast-paced and dynamic environment.
  • Traveling to meet with clients and tradeshows (up to 30%).

Mandatory requirements

  • Minimum BS or MS, preferred MBA or PhD. in Biotechnology, Biology, Chemistry or related field.
  • At least 4 years of a strong track record of closing business development contracts.
  • Preference will be given to candidates currently located in the US East Coast.
Apply for this position

Business Development Manager, North America West Coast

Posted 18th June 2021

Job description

We are recruiting a Business Development Manager for our growing Commercial Team. Our mission is to provide great science to clients in the Pharma and biotechnology industries. This individual will create client opportunities and establish partnerships with companies in striving for them to become key accounts in the territory. The ideal individual has a solid track record in managing relationships, external and internal, to exceed business development objectives.

This position is permanent and full-time, and to start immediately.

Job description

  • Develop and implement Business Development strategies for growing our cell line development services in human and animal health.
  • Identify opportunities and convert leads to expand our customer base. Our customers include those targeting any protein of interest in the fields of therapeutics and vaccine.
  • Perform effective business development and negotiation processes to establish a strong pipeline of accounts with cell line development contracts.
  • Promote the licensing of ExcellGene’s technologies and selling transfection-related products.
  • Manage business forecasts and budgetary input.
  • Work closely with other colleagues of the Commercial Team.

Required skills

  • Extensive experience in CRO, CRDO, or CDMO in identifying and working with decision makers in the biopharmaceutical and biotech industries.
  • Experience in market analysis, assessment of competitions, and a solid understanding of customers in the biopharmaceutical and biotech industries.
  • Strong knowledge in how to obtain leads and penetrate the CDMO markets.
  • Knowledge in cell line development, upstream, and downstream process developments.
  • Understanding of customer-centric business development and selling.
  • Ability to clearly communicate with customers and inside resources to accomplish objectives.
  • Ability to maintain accurate information in CRM and document related management tools.
  • Rigorousness, strong sense of discipline and attention to detail.
  • A hands-on approach to problem-solving and ability to flexibly adapt to changes in a fast-paced and dynamic environment.
  • Traveling to meet with clients and tradeshows (up to 30%).

Mandatory requirements

  • Minimum BS or MS, preferred MBA or PhD. in Biotechnology, Biology, Chemistry or related field.
  • At least 4 years of a strong track record of closing business development contracts.
  • Preference will be given to candidates currently located in the US West Coast.
Apply for this position

Submit a speculative application!

Posted 11th November 2020

We are now actively searching for exceptional individuals with high ethical standards that strive for scientific and technological excellence within a creative and team-oriented work environment. If this sounds interesting to you, we highly encourage you to send us your application through the form below, and ticking the box for 'speculative application'.

Please note that due to the open-ended nature of this type of application, we cannot guarantee follow-up communication. Thank you for your understanding.

Apply for this position

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