Careers

ExcellGene is a privately owned contract research, development and manufacturing organization (CDMO) based in Monthey, Switzerland and Boston, Massachusetts, USA. ExcellGene’s unique transient and stable protein expression technologies together with extensive knowledge and experience in the biotech field cover broad value chain for its clients: from DNA construction and transfection to bioprocess development of scalable and GMP-compliant protein production processes. ExcellGene’s technology is one of the most advanced for rapid production of recombinant proteins and up to several grams of product delivered within weeks.

Available roles


Senior Associate - Downstream Process Development (DSP biologics)

Posted 30th March 2022 This position is permanent and full-time, and to start immediately.

Job description

  • Development and optimization of DSP methods/processes for large scale/industrial production, implementation of new technologies, search/utilization of knowledge from scientific and technical literatur.
  • Planning and execution of Downstream process development of biosimilar/biologics drug substance in pre-clinical and clinical phases including development of scale-down models and scale-up procedures, reporting to the Head of DSP.
  • Execution of generic purifications at lab scale, mid-scale, and large-scale levels to deliver purified proteins according to expected specifications, including production of non-GMP lots for Tox studies.
  • Writing of protocols, reports, recording, management and evaluation of raw data/analyses/results, forming of sound scientific conclusions and providing suitable follow-up activities.
  • Leading DSP activities within project technical teams to deliver purified material for internal and/or external client.
  • Prompt communication of achievements, risks, issues in all areas and contribution to root cause investigations and troubleshooting.
  • Maintenance of high standards of quality, cleanliness, and organization within the laboratory environment.
  • Preparation of process development report and presentations for internal and/or external client meetings.

Required skills

  • Strong knowledge in downstream processing development concepts and implementation strategies (e.g., buffer preparation, viral inactivation/filtration, chromatography, TFF, Äkta systems) is required. Viral safety expertise is a plus.
  • Strong knowledge and solid hands-on experience in chromatography-based protein purification (e.g., affinity, ion-exchange, hydrophobic interactions, size-exclusion) and filtration-based separation methods for biologics.
  • Knowledge in high-throughput DSP development and DoE is a plus.
  • Scientifically curious, proactive, willing to learn, flexible, and with attention to details.
  • Rigorousness, strong sense of discipline and attention to details.
  • Problem-solving and hands-on approach to work.
  • Autonomous, able to work both independently and as part of a multicultural team within a matrix organization.
  • Flexibility and ability to adapt to changes in a fast-paced and dynamic environment.
  • Excellent communication skills. Good written and oral French and English languages.

Mandatory Requirements

  • Minimum B.Sc., M.Sc. preferred or PhD. in Biotechnology, Biology, Chemistry or related field.
  • At least 4 to 6 years of relevant experience in DSP process development with at least 2 in the biopharmaceutical industry.
Apply for this position

Research Associate — Analytics (HPLC and CE)

Posted 18th Nov 2021 This position is permanent and full-time, and to start immediately.

Job description

Under the supervision of the of the Head of Analytics, the candidate will actively participate in laboratory activities including but not limited to:
  • The operation of (U)HPLC and CE systems for protein analytics, including sample preparation, method/process troubleshooting and instrument preventive maintenance.
  • The design and execution of experimental assays using different analytical techniques and following established operating procedures, including data analysis and presentation.
  • The active support in the development of analytical methods and processes, the implementation of new technologies, the writing of protocols and technical reports according to corporate guidelines and quality standards.

Required skills

  • Excellent understanding of analytical chemistry and protein biochemistry.
  • Solid hands-on experience in protein analysis by liquid chromatography (HPLC andr UHPLC), with particular focus on affinity chromatography (protein A/G/L, etc.), SEC/GPC, RP and HILIC. Expertise in the operation of DLS/MALS detectors (including data analysis and interpretation) would be a strong plus.
  • Prior experience with capillary electrophoresis techniques (CE-SDS, cIEF, CZE, etc.) would be an advantage.
  • Excellent computer skills (MS Office package, basic statistical data analysis, familiar with the use of control and analytical software for chromatography instruments).
  • Scientific curiosity, proactiveness, initiative and willingness to learn.
  • Rigorousness, strong sense of discipline and attention to details.
  • Problem-solving and hands-on approach to work.
  • Autonomous and able to work both independently and as part of a multicultural team within a matrix organization.
  • Flexibility and ability to adapt to changes in a fast-paced and dynamic environment.
  • Excellent communication skills. Good written and oral French and English.

Mandatory requirements

  • Minimum B.Sc., M.Sc. or higher preferred in Biotechnology, Biology, Chemistry or related field.
  • Proven previous experience in analytics within R&D, analytical or QC laboratories (preferably 1-3 years within the industrial environment or in academia with at least 5 years of post-graduate work experience).
Apply for this position

Senior Associate — Down Stream Processing (DSP biologics)

Posted 2nd Nov 2021 This position is permanent and full-time, and to start immediately.

Job description

  • Planning and execution of DSP development/characterization of biosimilar/biologics drug substance in pre-clinical and clinical phases including development of scale-down models and scale-up procedures, reporting to the Head of DSP.
  • Execution of generic purifications at lab scale, mid-scale, and large-scale levels to deliver purified proteins according to expected specifications, including production of non-GMP lots for Tox studies.
  • Writing of protocols, reports, recording, management and evaluation of raw data/analyses/results, forming of sound scientific conclusions and providing suitable follow-up activities.
  • Development and optimization of DSP methods/processes, implementation of new technologies, search/utilization of knowledge from scientific and technical literature.
  • Leading DSP activities within project technical teams to deliver purified material for internal and/or external client.
  • Prompt communication of achievements, risks, issues in all areas and contribution to root cause investigations and troubleshooting.
  • Maintenance of high standards of quality, cleanliness, and organization within the laboratory environment.
  • Preparation of process development report and presentations for internal and/or external client meetings.

Required skills

  • Strong knowledge in downstream processing concepts and implementation strategies (e.g., buffer preparation, chromatography, TFF, Kr2i/Äkta systems).
  • Strong knowledge and solid hands-on experience in chromatography-based protein purification (e.g., affinity, ion-exchange, hydrophobic interactions, size-exclusion) and filtration-based separation methods for biologics.
  • Knowledge in high-throughput DSP development and DoE is a plus.
  • Scientifically curious, proactive, willing to learn, flexible, and with attention to details.
  • Rigorousness, strong sense of discipline and attention to details.
  • Problem-solving and hands-on approach to work.
  • Autonomous and able to work both independently and as part of a multicultural team within a matrix organization.
  • Flexibility and ability to adapt to changes in a fast-paced and dynamic environment.
  • Excellent communication skills. Good written and oral French and English languages.

Mandatory requirements

  • Minimum B.Sc., M.Sc. preferred or PhD. in Biotechnology, Biology, Chemistry or related field.
  • At least 4 years of relevant experience in DSP development and/or manufacturing.
Apply for this position

Business Development Manager, North America East Coast

Posted 18th June 2021

Job description

We are recruiting a Business Development Manager for our growing Commercial Team. Our mission is to provide great science to clients in the Pharma and biotechnology industries. This individual will create client opportunities and establish partnerships with companies in striving for them to become key accounts in the territory. The ideal individual has a solid track record in managing relationships, external and internal, to exceed business development objectives. This position is permanent and full-time, and to start immediately.

Job description

  • Develop and implement Business Development strategies for growing our cell line development services in human and animal health.
  • Identify opportunities and convert leads to expand our customer base. Our customers include those targeting any protein of interest in the fields of therapeutics and vaccine.
  • Perform effective business development and negotiation processes to establish a strong pipeline of accounts with cell line development contracts.
  • Promote the licensing of ExcellGene’s technologies and selling transfection-related products.
  • Manage business forecasts and budgetary input.
  • Work closely with other colleagues of the Commercial Team.

Required skills

  • Extensive experience in CRO, CRDO, or CDMO in identifying and working with decision makers in the biopharmaceutical and biotech industries.
  • Experience in market analysis, assessment of competitions, and a solid understanding of customers in the biopharmaceutical and biotech industries.
  • Strong knowledge in how to obtain leads and penetrate the CDMO markets.
  • Knowledge in cell line development, upstream, and downstream process developments.
  • Understanding of customer-centric business development and selling.
  • Ability to clearly communicate with customers and inside resources to accomplish objectives.
  • Ability to maintain accurate information in CRM and document related management tools.
  • Rigorousness, strong sense of discipline and attention to detail.
  • A hands-on approach to problem-solving and ability to flexibly adapt to changes in a fast-paced and dynamic environment.
  • Traveling to meet with clients and tradeshows (up to 30%).

Mandatory requirements

  • Minimum BS or MS, preferred MBA or PhD. in Biotechnology, Biology, Chemistry or related field.
  • At least 4 years of a strong track record of closing business development contracts.
  • Preference will be given to candidates currently located in the US East Coast.
Apply for this position

Submit a speculative application!

Posted 11th November 2020 We are now actively searching for exceptional individuals with high ethical standards that strive for scientific and technological excellence within a creative and team-oriented work environment. If this sounds interesting to you, we highly encourage you to send us your application through the form below, and ticking the box for 'speculative application'. Please note that due to the open-ended nature of this type of application, we cannot guarantee follow-up communication. Thank you for your understanding. Apply for this position

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